LyosenseTM. Lyophilisation process control. Poster presentation at: UK-PharmSci; 2010 Sept 1-3; Nottingham, UK

<p>Cite as : Smith G et al (2010) Lyosense^TM.Lyophilisation process control. Poster presentation at: UK-PharmSci; 2010 Sept 1-3; Nottingham, UK</p><p>The aim of this work is to develop an individual vial monitoring system (Lyosense™) for characterizing lyophile product characteristics and process end points to establish and control lyophilization regimes.<br></p><p>Lyosense^TM is a process analytical technology based on dielectric analysis of the lyophilization process. The system measures the pseudo-relaxation process associated with the interfacial polarization of the glass wall, through the resistance of the sample. This process undergoes characteristic changes in amplitude and peak frequency, such that the progress of freeze-drying and condition of the sample can be controlled.<br></p><p>Abstracts from the UK-Pharmsci Conference, 1–3 September 2010<br></p><div><div><div><em>Journal of Pharmacy and Pharmacology</em>, Volume 62, Issue 10, October 2010, Pages 1201–1516, <a href="https://doi.org/10.1111/j.2042-7158.2010.01178.x">https://doi.org/10.1111/j.2042-7158.2010.01178.x</a></div></div><div><div>Published: 03 September 2010</div></div></div>