Applications for Electrical Impedance Spectroscopy Process Analytical Technology (EIS-PAT) in Lyophilization Process Development. On-line presentation at Volanthen's 2nd Freeze-Drying Technology Summit February 17th-18th 2021

cite as :

Smith, G. (2021) Applications for Electrical Impedance Spectroscopy Process Analytical Technology (EIS-PAT) in Lyophilization Process Development. On-line presentation at Volanthen's 2nd Freeze-Drying Technology Summit February 17th-18th 2021

Topics covered by this talk:

- Electrical impedance and material attributes

- Non-invasive measurements (in process and for individual vials)

- Measurement frequency selection for ice fraction and unfrozen fraction

- Dielectric relaxation of ice : quantification of ice mass and calibration for ice temperature

- High frequency capacitance – a marker for the in-vial glass transition and other phase changes