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Applications for Electrical Impedance Spectroscopy Process Analytical Technology (EIS-PAT) in Lyophilization Process Development. On-line presentation at Volanthen's 2nd Freeze-Drying Technology Summit February 17th-18th 2021

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posted on 29.09.2021, 11:07 by Geoff SmithGeoff Smith
cite as :

Smith, G. (2021) Applications for Electrical Impedance Spectroscopy Process Analytical Technology (EIS-PAT) in Lyophilization Process Development. On-line presentation at Volanthen's 2nd Freeze-Drying Technology Summit February 17th-18th 2021

Topics covered by this talk:

- Electrical impedance and material attributes
- Non-invasive measurements (in process and for individual vials)
- Measurement frequency selection for ice fraction and unfrozen fraction
- Dielectric relaxation of ice : quantification of ice mass and calibration for ice temperature
- High frequency capacitance – a marker for the in-vial glass transition and other phase changes

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