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Smith G (2021) Form Dev and Drug Delivery Sept 20-21.pdf (2.97 MB)
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Non-invasive impedance spectroscopy for single-vial PAT in biopharmaceutical freeze-drying. Podium presentation at Oxford Global Formulation and Delivery UK. September 21-23, 2021
Version 2 2021-09-29, 11:07
Version 1 2021-09-23, 09:20
presentation
posted on 2021-09-29, 11:07 authored by Geoff SmithGeoff Smith, paul Matejtschukpaul Matejtschuk, Pathum WijesekaraPathum Wijesekaracite as :
Smith, G. (2021) Non-invasive impedance spectroscopy for single-vial PAT in biopharmaceutical freeze-drying. Podium presentation at Oxford Global Formulation and Delivery UK. September 21-23
This presentation introduces the technology known as through vial impedance spectroscopy (TVIS) with a description of the hardware and the polarization processes that can be studied before describing applications for temperature prediction, the in-vial characterization of phase behaviour, and the determination of the end of sublimation-drying in a single vial
The work was undertaken in collaboration with Dr Paul Matejtschuk from the National Institute of Biological Standards and Control (NIBSC, South Mimms) and co-authored by Pathum Wijesekara (De Montfort University PhD student).
