DOCUMENT
Smith G (2022) Pharmaceutical Processing (Figshare upload).pdf (3.04 MB)
PRESENTATION
Smith G (2022) Pharmaceutical Processing (Figshare upload).pptx (112.2 MB)
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Process Analytical Technology for Lyophilization Cycle Development: Applications for electrical impedance spectroscopy. on-line presentation at Innovatrix Pharmaceutical Processing Summit. 26-27 January 2022
Cite as : Smith, G. (2022) Process Analytical Technology for Lyophilization Cycle Development: Applications for Electrical impedance spectroscopy. on-line presentation at Innovatrix Pharmaceutical Processing Summit. 26-27 January 2022 10.21253/DMU.19625841
Topics covered by this talk:
Introduction to freeze-drying and PAT
Introduction to TVIS
The 'true' primary drying end point
Separation between sublimation (primary drying)
and diffusive desorption (secondary drying)
The impact of phase states (crystalline vs amorphous) on the end point profile
