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Process Analytical Technology for Lyophilization Cycle Development: Applications for electrical impedance spectroscopy. on-line presentation at Innovatrix Pharmaceutical Processing Summit. 26-27 January 2022

presentation
posted on 2022-05-11, 11:26 authored by Geoff SmithGeoff Smith
<p>Cite as : Smith, G. (2022) Process Analytical Technology for Lyophilization Cycle Development: Applications for Electrical impedance spectroscopy. on-line presentation at Innovatrix Pharmaceutical Processing Summit. 26-27 January 2022  <a href="https://doi.org/10.21253/DMU.19625841" target="_blank">10.21253/DMU.19625841</a></p> <p><br></p> <p>Topics covered by this talk:</p> <p><br></p> <p>Introduction to freeze-drying and PAT</p> <p>Introduction to TVIS</p> <p>The 'true' primary drying end point</p> <p>Separation between sublimation (primary drying)</p> <p>and diffusive desorption (secondary drying) </p> <p>The impact of phase states (crystalline vs amorphous) on the end point profile</p> <p><br></p> <p><br></p>

Funding

Innovate-UK grant 100527 (AtlasBio)

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