The Application of Through Vial Impedance Spectroscopy (TVIS) for Process Parameter Determination in Freeze Drying Method Development. PDA Europe Pharmaceutical Freeze Drying Technology; Sept 27-28; Strasbourg, France
cite as: <div>Smith G. (2016) The Application of Through Vial Impedance Spectroscopy (TVIS) for Process Parameter Determination in Freeze Drying Method Development. Podium presentation at PDA Europe Pharmaceutical Freeze Drying Technology; 2016 Sept 27-28, Strasbourg, France<br></div><div><div><br></div><div>The presentation starts with a description of the through vial impedance spectroscopy (TVIS) and the measurement system before going on to describe applications in the determination of various process parameters and related phenomena:</div><div><div> Vial heat transfer coefficient (K<sub>V</sub>)</div><div> Dry layer resistance (R<sub>P</sub>)</div><div> Ice nucleation (onset of ice growth)</div><div> Glass transition</div><div> Eutectic crystallization</div><div> Collapse</div></div><div><br></div><div><br></div></div>
