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Changing shape of the ice mass. Observations by TVIS (through-vial impedance spectroscopy)

figure posted on 2024-11-25

Geoff Smith

Cake appearance of freeze-dried products

figure posted on 2024-11-25

Geoff Smith

Principal heat transfer mechanisms from shelf to base of the vial

figure posted on 2024-11-25

Geoff Smith

collection:
Freeze-drying (lyophilization) figures

posted on 2024-05-08

Geoff Smith

Smith G (2023) Electrical impedance PAT for biotherapeutic freeze-drying. Marcus Evans 14th Biologics Formulation, Development And Drug Delivery Sept 14-15th

presentation posted on 2023-09-21

Geoff Smith

FIGURE

Drawing of a 10R vial containing a frozen solution undergoing the process of ice sublimation, during the primary drying stage of a freeze-drying cycle.

figure posted on 2023-08-02

Geoff Smith

FIGURE

Electricity (Ohm's law, charging of a capacitor, dc and ac theory, VI phasors and ciruit elements) cite as : Smith, G. (2023). Electricity (Ohm's law, charging of a capacitor, dc and ac theory, VI phasors and ciruit elements). Figshare.

figure posted on 2023-07-07

Geoff Smith

Electrical impedance and measurement: The theory behind the technique of through-vial impedance spectroscopy (TVIS)

chapter posted on 2023-04-06

Geoff Smith

Relationship between input parameters and process parameters of a freeze-drying cycle

figure posted on 2023-03-16

Geoff Smith

ISO design standards for glass vials

figure posted on 2023-03-01

Geoff Smith

Phase diagram of water-sucrose system

figure posted on 2023-02-22

Geoff Smith

Primary drying model

figure posted on 2023-02-22

Geoff Smith

A thermodynamic system: Sublimation of ice from a glass vial

figure posted on 2023-02-22

Geoff Smith

Primary drying profile for 15% IgG formulation

figure posted on 2023-02-17

Geoff Smith

Product resistance to vapour flow

figure posted on 2023-02-17

Geoff Smith

Phase diagram of ice demonstrating the process of sublimation

figure posted on 2023-02-17

Geoff Smith

Phase diagram of water illustrating the process of boiling

figure posted on 2023-02-17

Geoff Smith

Example freezing cycle

figure posted on 2023-02-17

Geoff Smith

Freeze-drying (lyophilisation) cycle recipe

figure posted on 2023-02-17

Geoff Smith

Simplified schematic of a freeze-dryer

figure posted on 2023-02-17

Geoff Smith

Schematic of a lyophilization cycle

figure posted on 2023-02-17

Geoff Smith

In situ characterization of phase separation in PVP dextran solutions using impedance spectroscopy

conference contribution posted on 2023-01-26

Smith, G. (2022) Freeze-drying for the stabilization of drug products: Recent developments in process analytical technologies. Podium presentation at Oxford Global Formulation and Delivery UK. London 5-6 May

presentation posted on 2022-12-15

Geoff Smith

Smith, G (2022) Process analytical technology (PAT) for sublimation end point determination (primary drying stage) On-line presentation at Oxford Global Pharmaceutical Lyophilization Symposium. 8 December 2022

presentation posted on 2022-12-15

Geoff Smith

Smith, G. (2022) A determination of the true sublimation end point by through-vial Impedance spectroscopy. Podium presentation at Lyotalk, 21-22 July, Dublin

conference contribution posted on 2022-07-20

Geoff Smith

Smith, G. (2022). The determination of the true sublimation end point by through-vial Impedance spectroscopy. Podium presentation at Lyotalk, 19-20 May, Amsterdam

conference contribution posted on 2022-07-20

Geoff Smith

Process Analytical Technology for Lyophilization Cycle Development: Applications for electrical impedance spectroscopy. on-line presentation at Innovatrix Pharmaceutical Processing Summit. 26-27 January 2022

presentation posted on 2022-05-11

Geoff Smith

Non invasive impedance spectroscopy for single vial PAT in biopharmaceutical freeze drying. On-line presentation at Pharma Manufacturing Europe. 1-2 December 2021

presentation posted on 2022-05-11

Geoff Smith

DATASET

Observations on the Changing Shape of the Ice Mass and the Determination of the Sublimation End Point in Freeze-Drying: An Application for Through-Vial Impedance Spectroscopy (TVIS)

dataset posted on 2021-11-03

LyosenseTM: A method for controlling and/or monitoring process parameters of the lyophilization process

conference contribution posted on 2021-10-07

Geoff Smith

LyosenseTM. Lyophilisation process control. Poster presentation at: UK-PharmSci; 2010 Sept 1-3; Nottingham, UK

conference contribution posted on 2021-10-07

Geoff Smith